Premium
Dielectric response of frustrated water down to a single‐molecule contribution
Author(s) -
Fernández Ariel
Publication year - 2017
Publication title -
annalen der physik
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 68
eISSN - 1521-3889
pISSN - 0003-3804
DOI - 10.1002/andp.201600373
Subject(s) - dielectric , dielectric response , molecule , debye , polarization (electrochemistry) , materials science , hydrogen bond , dielectric spectroscopy , frustration , nanoscopic scale , condensed matter physics , chemical physics , physics , nanotechnology , chemistry , quantum mechanics , optoelectronics , electrochemistry , electrode
A theory of dielectric response of water under nanoscale confinement was long overdue. This work addresses the problem by establishing a relation between dielectric response and hydrogen‐bond frustration subsumed in a non‐Debye polarization term. The results hold down to the single‐molecule contribution and are validated vis‐à‐vis experimental measurements on a system where dielectric modulation entails removal of a single water molecule. The frustrated dielectric response down to molecular scales is assessed by contrasting two enantiomeric ligands in association with the same protein, with the complexes differing in the removal of a single interfacial water molecule.