Open AccessCell‐Based Bio‐Hybrid Delivery System for Disease Treatments
Author(s) -
Li Chu-Xin,
Qi Yong-Dan,
Feng Jun,
Zhang Xian-Zheng
Publication year - 2021
Publication title -
advanced nanobiomed research
Language(s) - English
Resource type - Journals
ISSN - 2699-9307
DOI - 10.1002/anbr.202000052
Subject(s) - biochemical engineering , nanotechnology , biocompatibility , artificial cell , disease treatment , delivery system , computer science , hybrid system , biology , materials science , engineering , medicine , biomedical engineering , intensive care medicine , membrane , genetics , machine learning , metallurgy
Live cells are implicated in diverse biological processes, including nutrient transport and removal of foreign substances. Their intelligent biofunctions with complex mechanisms cannot be replicated at all in man‐made materials despite the significant advance in material design. Taking advantages of their biocompatibility and biotropic capability, various live cells have been developed as a kind of special carriers for the on‐demand delivery of therapeutic and diagnostic agents in recent years. Furthermore, synthetic materials can be integrated with live cells to provide bio‐hybrid systems that inherit advantages from both the synthetic particles and the natural cells. Herein, recent strategies and advances in cell‐based bio‐hybrid delivery systems for disease treatment are summarized. Challenges and opportunities in this field are also discussed.