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Muscle fiber immaturity and inactivity reduce myonecrosis in duchenne muscular dystrophy
Author(s) -
Kimura Shigemi,
Sugino Shigeto,
Ohtani Yoshinobu,
Matsukura Makoto,
Nishino Ichizo,
Ikezawa Makoto,
Sakata Ayako,
Kondo Yuichi,
Yoshioka Kowashi,
Huard Johnny,
aka Ikuya,
Miike Teruhisa
Publication year - 1998
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410440618
Subject(s) - duchenne muscular dystrophy , muscle biopsy , medicine , muscular dystrophy , myopathy , dystrophin , muscle fibre , biopsy , physical medicine and rehabilitation , pathology , anatomy , skeletal muscle
We report on the first case of X‐linked recessive myotubular myopathy (MTM1) coinciding with Duchenne muscular dystrophy (DMD). The muscle biopsy specimens of the patient show only the characteristic findings of MTM1, without the findings of DMD. We theorize that this was caused by the muscle fiber immaturity and inactivity.