Premium
Cephalosporin‐induced recurrent aseptic meningitis
Author(s) -
Creel George B.,
Hurtt Mark
Publication year - 1995
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410370617
Subject(s) - aseptic meningitis , cephalosporin , meningitis , medicine , aseptic processing , antibiotics , intensive care medicine , microbiology and biotechnology , pediatrics , surgery , biology
Abstract A 66‐year‐old woman had several episodes of aseptic meningitis associated with exposure to cephalexin, cefazolin, and ceftazidime. The cerebrospinal fluid IgG index was elevated, specific IgG‐ceftazidime binding was shown, and skin allergy testing with cefazolin provoked a recurrence of meningitis. We postulate an acute hypersensitivity reaction involving an antigen‐specific humoral immune response.