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Visual system abnormalities in adrenomyeloneuropathy
Author(s) -
Kaplan Peter W.,
Kruse Bernd,
Tusa Ronald J.,
Shankroff Jan,
Rignani Joellen,
Moser Hugo W.
Publication year - 1995
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410370419
Subject(s) - geniculate body , geniculate , visual system , magnetic resonance imaging , visual cortex , neuroscience , medicine , optic nerve , optic tract , anatomy , psychology , radiology , nucleus
We studied the visual system in 59 men with adrenomyeloneuropathy. Pattern‐reversal visual evoked potentials, magnetic resonance imaging, and clinical examination revealed that visual pathways are affected in 63% of patients, involving the optic discs, optic nerves, lateral geniculate bodies, optic radiations, and parietooccipital cortex. This indicates both primary demyelination of the optic nerves and discs, and more diffuse involvement of postchiasmal structures.