Premium
Pain modulation and the action of analgesic medications
Author(s) -
Fields Howard
Publication year - 1994
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410350713
Subject(s) - analgesic , tricyclic , medicine , neuralgia , neuropathic pain , anesthesia , peripheral , central nervous system , neuroscience , pharmacology , psychology
A general approach to improving the treatment of patients with post‐herpetic neuralgia is outlined. Pain‐generating processes initiated by injury to peripheral nerve and new treatments that target these processes are discussed. Another described approach is to use knowledge of central nervous system pain‐modulating networks to improve the effectiveness of centrally acting analgesics such as opioids and tricyclic antidepressants.