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Cerebral lymphoma presenting as a nonenhancing lesion on computed tomographic/ magnetic resonance scan
Author(s) -
DeAngelis Lisa M.
Publication year - 1993
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410330313
Subject(s) - magnetic resonance imaging , computed tomographic , medicine , lymphoma , lesion , computed tomography , radiology , mass/lesion , contrast enhancement , nuclear medicine , pathology
Cerebral lymphoma is usually indentified on computered tomographic/magnetic resonance scan as a homogeneously contrast‐enhancing periventricular mass lession. We present 10 patients with cerebrllymphoma who had nonenhancing tumor on computed tomographic (2 patients) or magnetic resonance scan (8 patients) either at the time of diagnosis or recurrence. The absence of enhancement caused diagnostic delay in all patients and suggests that tumor resides behind an intact blood brain barrier, raising important therapeutic implications in the design of chemotherapeutic regimens.