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Delayed peripartum vasculopathy: Cerebral eclampsia revisited
Author(s) -
Raps Eric C.,
Galetta Steven L.,
Broderick Magie,
Atlas Scott
Publication year - 1993
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410330215
Subject(s) - medicine , eclampsia , vasospasm , magnetic resonance imaging , white matter , postpartum period , radiology , edema , proteinuria , brain edema , pregnancy , cardiology , subarachnoid hemorrhage , kidney , genetics , biology
Over a 2‐Year Period, we treated 4 postpartum patients with acute neurologic problems appearing 4 to 9 days after delivery. Three patients either had no proteinuria or edema and therfore did not meet all accepted clinical criteria for the diagnosis of eclampisa. Magnetic resonance imaging (MRI) of the brain in all patients demonstrated high‐signal foci most prominent in the parietooccipital regions and the subcortical white matter. Cerebral angiogram in 2 patients revealed diffuse vasospasm. In 3 patients, MRI abnormalities resolved. MRI and angiographic abnormalities in our patients are identical to those of patients meeting accepted criteria for eclampisa. Our experience suggest that the current criteria for the diagnosis of eclampsia are too stingent, both in terms of clinical picture and days postpartum to cerebral mainfestations.