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Signal loss in the motor cortex on magnetic resonance images in amyotrophic lateral sclerosis
Author(s) -
Ishikawa Kinya,
Nagura Hiroshi,
Yokota Tsukasa,
Yamanouchi Hiroshi
Publication year - 1993
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410330214
Subject(s) - amyotrophic lateral sclerosis , magnetic resonance imaging , motor cortex , medicine , primary motor cortex , neuroscience , abnormality , cortex (anatomy) , functional magnetic resonance imaging , pathological , psychology , pathology , radiology , psychiatry , disease , stimulation
Three of 7 patients with amyotrophic lateral sclerosis had bilateral signal loss confined to the motor cortex on T2‐weighted magnetic resonance images. None of the control subjects had this abnormality. Although not present in every patient, this finding might reflect the primary pathological process of the motor cortex in amyotrophic lateral sclerosis.