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Chronic encephalitis (rasmussen's syndrome) and ipsilateral uveitis
Author(s) -
Harvey A. Simon,
Andermann Frederick,
Hopkins Ian J.,
Kirkham Trevor H.,
Berkovic Samuel F.
Publication year - 1992
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410320621
Subject(s) - uveitis , medicine , encephalitis , virology , ophthalmology , virus
Two children are reported with acute uveitis during the early progressive phase of chronic encephalitis (Rasmussen's syndrome). In both children, the side of the uveitis was ipsilateral to the side of cerebral inflammation, although in 1 child there were milder inflammatory changes in the contralateral eye. This association adds weight to the viral hypothesis of chronic encephalitis and raises the possibility of primary ocular infection and neurotropic spread to the brain.