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Cerebrovascular abnormalities in pediatric stroke: Assessment using parenchymal and angiographic magnetic resonance imaging
Author(s) -
Wiznitzer Max,
Masaryk Thomas J.
Publication year - 1991
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410290603
Subject(s) - medicine , magnetic resonance imaging , magnetic resonance angiography , radiology , angiography , stroke (engine) , stenosis , infarction , cardiology , myocardial infarction , mechanical engineering , engineering
Three‐dimensional (volume) magnetic resonance angiography is a noninvasive technique the images the intracranial and cervical arterial vasculature without contrast agents. Twenty‐four children with strokes had combined parenchymal magnetic resonance imaging and magnetic resonance angiography 1 day to 4 years after acute presentation. Eight had had prior intra‐arterial angiography. Eighteen magnetic resonance angiographic studies showed arterial stenosis or occlusion in the vascular distribution of magnetic resonance image‐defined brain infarction and, in 7 children, in the same location as previously defined abnormalities on intra‐arterial angiography. One child had a normal intra‐arterial angiogram and magnetic resonance angiogram. The other 5 children with normal magnetic resonance angiographic studies included 3 with presumed embolic disease, 1 with meningitis, and 1 with Crohn's disease‐related vasculitis. Collateral flow patterns could be determined in 4 children. Artifact presenting as filling defects in vessels was present in 10 studies, but did not interfere with interpretation of 8 studies. Combined magnetic resonance imaging/magnetic resonance angiography provides a screening technique to evaluate noninvasively brain parenchyma and vasculature in children with suspected large‐vessel abnormalities, allowing selection for intra‐arterial angiography and vasculature in children with suspected large‐vessel abnormalities, allowing selection for intra‐arterial angiography and serial monitoring of vascular abnormalities over time and during therapeutic intervention.