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Cranial neuropathy associated with primary amyloidosis
Author(s) -
Traynor Ann E.,
Gertz Morie A.,
Kyle Robert A.
Publication year - 1991
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410290421
Subject(s) - amyloidosis , medicine , proteinuria , differential diagnosis , primary systemic amyloidosis , pathology , biopsy , amyloid (mycology) , dermatology , kidney , systemic disease , disease
We report 6 patients for whom cranial neuropathy was a major manifestation of primary amyloidosis. In 3 of the 6, multiple cranial nerves were involved. All had tissue biopsy documentation of amyloidosis. In 2, nerve biopsy also confirmed amyloidosis. All had renal involvement manifested by proteinuria. Primary systemic amyloidosis must be considered in the differential diagnosis of cranial neuropathy, especially when proteinuria is present.