z-logo
Premium
Brain microemboli during cardiac surgery or aortography
Author(s) -
Moody D M.,
Bell M. A.,
Challa V. R.,
Johnston W. E.,
Prough D. S.
Publication year - 1990
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410280403
Subject(s) - cardiopulmonary bypass , aortography , medicine , cardiac surgery , angiography , radiology , cardiology , surgery , aorta
We have observed many focal dilatations or very small aneurysms in terminal arterioles and capillaries of 4 of 5 patients and 6 dogs who had recently undergone cardiopulmonary bypass. A smaller number of sausagelike dilatations distended medium‐sized arterioles. Two other patients had a small number of the same microvascular changes following proximal aortography. Thirty‐four patients and 6 dogs not undergoing cardiopulmonary bypass had none. (A 35th patient who had not undergone cardiopulmonary bypass or aortography showed a small number of dilatations; mediastinal air was a suggested source.) Some of the dilatations exhibited various forms of birefringence. Because most of the dilatations appear empty, we speculate that they are the sites of gas bubbles or fat emboli that have been removed by the solvents used in processing. These microvascular events, occurring only in conjunction with major arterial interventions, may be the anatomical correlate of the neurological deficits or moderate to severe intellectual dysfunction seen in at least 24% of patients after cardiac surgical procedures assisted by cardiopulmonary bypass.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here