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Successful chemotherapy for newly diagnosed aggressive oligodendroglioma
Author(s) -
Macdonald David R.,
Gaspar Laurie E.,
Cairncross J. Gregory
Publication year - 1990
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410270519
Subject(s) - oligodendroglioma , medicine , chemotherapy , radiation therapy , regimen , induction chemotherapy , surgery , oncology , glioma , astrocytoma , cancer research
We treated 3 patients with newly diagnosed aggressive oligodendroglioma with chemotherapy prior to radiotherapy and observed responses. All had residual or progressive tumor following initial surgery. We used a combination called PCV‐3 because recurrent anaplastic oligodendroglioma responds predictably to this regimen. Chemotherapy for response induction followed by radiotherapy for consolidation is feasible and effective initial treatment for this tumor.