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Magnetic resonance imaging morphology of the corpus callosum in monozygotic twins
Author(s) -
Oppenheim Jeffrey S.,
Skerry John E.,
Gazzaniga Michael S.
Publication year - 1989
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410260117
Subject(s) - corpus callosum , magnetic resonance imaging , morphology (biology) , medicine , brain morphometry , nuclear magnetic resonance , anatomy , psychology , biology , radiology , physics , zoology
Recent reports describe wide variations in the size and shape of the human corpus callosum. To investigate genetic influences on this variability, magnetic resonance images from 5 pairs of monozygotic twins and 10 unrelated control subjects were analyzed. Measurements of size and shape revealed greater similarity in twin pairs than in randomly paired controls. The results are consistent with the view that the anatomy of the corpus callosum, while clearly influenced by nongenetic factors, is under considerable genetic control.