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Inflammatory lesions of peripheral nerve in a patient with human T‐lymphotropic virus type I‐associated myelopathy
Author(s) -
Said Gérard,
GoulonGoeau Catherine,
Lacroix Catherine,
Fève Anaic,
Descamps Hélène,
Fouchard Marchie
Publication year - 1988
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410240218
Subject(s) - tropical spastic paraparesis , wallerian degeneration , myelopathy , medicine , pathology , human t lymphotropic virus , peripheral nervous system , nerve biopsy , peripheral neuropathy , central nervous system , spinal cord , endocrinology , psychiatry , diabetes mellitus
In a patient with tropical spastic paraparesis associated with a positive titer for human T‐lymphotropic virus type I, electrophysiological study detected a mixed, axonal and demyelinating, multifocal neuropathy. Perineural and perivascular infiltrates, moderate axon loss, wallerian degeneration, and demyelinating lesions of isolated fibers were present in the nerve biopsy specimen. These inflammatory lesions resembled those found in the central nervous system of patients with tropical spastic paraparesis.