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HTLV‐I‐Like viral particles in spinal cord cells in jamaican tropical spastic paraparesis
Author(s) -
Liberski Pawel P.,
RodgersJohnson Pamela,
Char Guendra,
Piccardo Pedro,
Gibbs Clarence J.,
Gajdusek D. Carleton
Publication year - 1988
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410230741
Subject(s) - tropical spastic paraparesis , spinal cord , virology , human t lymphotropic virus , virus , electron microscope , medicine , pathology , spasticity , biology , immunology , myelopathy , physics , optics , psychiatry , physical therapy
Viral‐like particles morphologically identical to human T‐lymphotropic virus type I or II, but distinct from human T‐lymphotropic virus type III, have been seen by electron microscopy in spinal cord tissue from a Jamaican tropical spastic paraparesis patient who was known to be positive for human T‐lymphotropic virus I antibody before death. This is the first electron microscopy report on a patient from an endemic tropical spastic paraparesis region.