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Neuropsychiatric consequences of AIDS
Author(s) -
Rubinow David R.,
Berrettini Christine H.,
Brouwers Pim,
Lane H. Clifford
Publication year - 1988
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410230710
Subject(s) - medicine , neuropsychology , human immunodeficiency virus (hiv) , neuropsychological test , cognition , immunodeficiency , viral disease , chronic fatigue syndrome , immunology , pediatrics , psychiatry , immune system
As part of a study in progress, neuropsychological tests have been administered to 13 patients with clinical acquired immunodeficiency syndrome, 9 human immunodeficiency virus–seropositive patients, 4 seropositive patients with chronic active hepatitis, 5 seronegative patients with chronic active hepatitis, and 6 healthy controls. Consistent with findings in earlier patient and control groups, the acquired immunodeficiency syndrome patients had substantially lower scores on a variety of cognitive tests. Although the acquired immunodeficiency syndrome group is not education‐matched at present, the results are nonetheless consistent with impairments of language function and timed, self‐paced performance. Test results obtained may reflect focal and global cognitive impairment as well as motivational decrements in patients with the acquired immunodeficiency syndrome relative to seropositive patients or controls.