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Magnetic resonance imaging in amyotrophic lateral sclerosis
Author(s) -
Goodin Douglas S.,
Rowley Howard A.,
Olney Richard K.
Publication year - 1988
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410230424
Subject(s) - amyotrophic lateral sclerosis , corona radiata (embryology) , internal capsule , magnetic resonance imaging , white matter , medicine , pons , pathology , anatomy , radiology , disease , cumulus oophorus , ovarian follicle , hormone
Magnetic resonance imaging (MRI) was used in 5 patients with clinically definite amyotrophic lateral sclerosis to determine the frequency of central white matter abnormalities. Two patients had symmetrical areas of increased signal intensity seen on MRI extending from the cortex, through the corona radiata, posterior limb of the internal capsule, and cerebral peduncles into the pons. These MRI abnormalities presumably relate to the pathological changes observed by others in the central white matter of patients with amyotrophic lateral sclerosis.