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Central pontine myelinolysis after rapid correction of hyponatremia: A magnetic resonance imaging study
Author(s) -
Brunner John E.,
Redmond Janice M.,
Haggar Allan M.,
Elias Stanton B.
Publication year - 1988
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410230413
Subject(s) - central pontine myelinolysis , hyponatremia , pons , magnetic resonance imaging , encephalopathy , medicine , lesion , radiology , pathology
We describe a patient with severe hyponatremia (serum sodium 94 mmol/L) who developed encephalopathy and decorticate posturing after a 29 mmol/L rise in serum sodium concentration during the first 24 hours of correction. High‐resolution computed tomography of the pons was normal during the first, second, and twelfth weeks of the illness. Subsequent magnetic resonance imaging revealed a pontine lesion consistent with central pontine myelinolysis.