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Clinical and electrophysiological studies of human immunodeficiency virus—seropositive men without AIDS
Author(s) -
Smith T.,
Jakobsen J.,
Gaub J.,
HelwegLarsen S.,
Trojaborg W.
Publication year - 1988
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410230313
Subject(s) - medicine , spinal cord , somatosensory evoked potential , ataxia , brainstem , electrophysiology , nerve root , lumbar , nerve conduction velocity , ganglion , anatomy , pathology , anesthesia , psychiatry
Motor weakness and ataxia of lower limbs and abnormalities of somatosensory evoked potentials occur in many patients with the acquired immunodeficiency syndrome (AIDS). We studied 15 human immunodeficiency virus‐seropositive subjects without AIDS and found no clinical neurological abnormalities. The mean latency of the brainstem auditory evoked potential (peak V) was increased, suggesting a central defect. Despite normal peripheral nerve conduction along the tibial nerve, the mean latency of the spinal cord potential of the twelfth thoracic vertebra was increased compared with normal, possibly indicating an incipient conduction defect at or near the spinal root ganglion or lumbar spinal cord.