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Multifocal cytomegalovirus encephalitis in AIDS
Author(s) -
Masdeu J. C.,
Small C. B.,
Weiss L.,
Elkin C. M.,
Llena J.,
MesaTejada R.
Publication year - 1988
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410230118
Subject(s) - medicine , cytomegalovirus , magnetic resonance imaging , pathology , encephalitis , computed tomography , disease , radiology , viral disease , virology , herpesviridae , human immunodeficiency virus (hiv) , virus
A 43‐year‐old man with the acquired immunodeficiency syndrome had clinical evidence of multifocal disease of the brain, but computed tomography was negative. Magnetic resonance imaging revealed multifocal lesions, histologically proven to be caused by cytomegalovirus. Therapy with 9{2‐hydroxy‐1‐(hydroxymethyl) ethoxymethyl} guanine (BW B759U) resulted in stabilization of the patient's clinical disease and radiographic improvement of the lesions.