Evidence that amphetamine with physical therapy promotes recovery of motor function in stroke patients | Zendy

Crisostomo Edgardo A. | Zendy; Duncan Pamela W. | Zendy; Propst Martha | Zendy; Dawson Deborah V. | Zendy; Davis James N. | Zendy

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Evidence that amphetamine with physical therapy promotes recovery of motor function in stroke patients

Author(s) -

Crisostomo Edgardo A.,

Duncan Pamela W.,

Propst Martha,

Dawson Deborah V.,

Davis James N.

Publication year - 1988

Publication title -

annals of neurology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.764

H-Index - 296

eISSN - 1531-8249

pISSN - 0364-5134

DOI - 10.1002/ana.410230117

Subject(s) - amphetamine , stroke (engine) , placebo , rehabilitation , physical medicine and rehabilitation , medicine , motor function , cerebral infarction , physical therapy , motor activity , psychology , anesthesia , psychiatry , mechanical engineering , alternative medicine , ischemia , pathology , engineering , dopamine

We conducted a double‐blind pilot study of 8 patients with established cerebral infarction to evaluate the effect of a single dose of amphetamine on recovery of motor function using the Fugl‐Meyer scale. Four patients received amphetamine; the rest were given placebo. All underwent a session of physical therapy. Patients treated with amphetamine obtained greater increments in motor scores than the controls. Along with animal studies, these findings may allow the development of a pharmacological approach to stroke rehabilitation.

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