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Magnetic resonance imaging in multiple sclerosis: Decreased signal in thalamus and putamen
Author(s) -
Drayer Burton P.,
Burger Peter,
Hurwitz Barrie,
Dawson Deborah,
Cain John,
Leong Jackie,
Herfkens Robert,
Allan Johnson G.
Publication year - 1987
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410220418
Subject(s) - putamen , thalamus , magnetic resonance imaging , white matter , nuclear magnetic resonance , multiple sclerosis , medicine , intensity (physics) , t2 relaxation , nuclear medicine , pathology , radiology , physics , quantum mechanics , psychiatry
High‐field strength (1.5 Tesla) magnetic resonance imaging in 15 patients with multiple and extensive white‐matter lesions and clinically definite multiple sclerosis delineated a previously underscribed finding of abnormally Decemberreased signal intensity on T2‐weighted images in the thalamus and putamen. The Decemberreased signal intensity (preferential Decemberreased T2 relaxation time) is most likely to be related to abnormally increased iron accumulation causing local magnetic field heterogeneities.