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Effect of levodopa treatment on contrast sensitivity in Parkinson's disease
Author(s) -
Bulens C.,
Meerwaldt J. D.,
Van der Wildt G. J.,
Van Deursen J. B. P.
Publication year - 1987
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410220313
Subject(s) - levodopa , contrast (vision) , parkinson's disease , medicine , dopamine , sensitivity (control systems) , disease , physics , electronic engineering , optics , engineering
We studies contrast sensitivity function in 10 parkinsonian patients before and after levodopa treatment. Pretreatment contrast sensitivity function was abnormal in 16 of the 20 eyes. After treatment, only high‐frequency loss was observed in 6 eyes. All other types of deficit disappeared under treatment. These changes of contrast sensitivity function following treatment suggest that dopamine is functional transmitter in the visual pathways.