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Magnetic resonance imaging in temporal lobe epilepsy: Pathological correlations
Author(s) -
Kuzniecky Ruben,
de la Sayette Vincent,
Ethier Roméo,
Melanson Denis,
Andermann Frederick,
Berkovic Samuel,
Robitaille Yves,
Olivier André,
Peters Terence,
Feindel William
Publication year - 1987
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410220310
Subject(s) - gliosis , temporal lobe , magnetic resonance imaging , epilepsy , pathological , medicine , neocortex , pathology , radiology , central nervous system disease , surgery , psychiatry
A retrospective single‐blind study assessing the value of magnetic resonance imaging (MRI) in 48 patients treated surgically for temporal lobe epilepsy was carried out. The imaging findings were correlated with the surgical findings in all cases. Abnormal MRI signals were detected in 34 of 48 (71%) epileptic patients and in 3 of 48 (6.2%) normal or disease control subjects. Twelve patients had structural foreign‐tissue lesions, all detected by MRI. Of 14 patients with severe gliosis of the neocortex and/or mesial temporal structures, 11 had abnormal MRI scans. In patients with mild or moderate gliosis of mesial temporal structures, 6 of 12 had abnormal MRI scans. These results indicate that MRI is a sensitive technique for localizing foreign‐tissue lesions, mesial temporal sclerosis, and gliosis in patients with intractable temporal lobe seizures.