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Mononeuritis multiplex in Waldenström's macroglobulinemia
Author(s) -
Lamarca Josep,
Casquero Pilar,
Pou Adolf
Publication year - 1987
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410220213
Subject(s) - mononeuritis multiplex , macroglobulinemia , medicine , waldenstrom macroglobulinemia , pathology , sural nerve , dermatology , vasculitis , lymphoma , multiple myeloma , disease
Abstract We describe a patient with mononeuritis multiplex who had cranial nerve involvement in association with Waldenström's macroglobulinemia. Sural nerve biopsy showed abundant endoneurial granulofibrillary deposits related to microangiopathic changes. These changes were distributed in a multifocal pattern among the fascicles. Immunohistochemistry demonstrated the IgM nature of the deposit located in the endoneurial interstitium.