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IgG heavy‐chain (Gm) allotypes in demyelinating polyneuropathy associated with MAG‐binding monoclonal IgM autoantibodies
Author(s) -
Kahn Sidney N.,
Pandey Janardan P.
Publication year - 1987
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410210516
Subject(s) - autoantibody , polyneuropathy , myelin associated glycoprotein , monoclonal , medicine , monoclonal antibody , immunology , myelin sheath , chronic inflammatory demyelinating polyneuropathy , population , phenotype , myelin , antibody , pathology , biology , genetics , central nervous system , environmental health , gene
IgG heavy‐chain (Gm) allotypes were determined in 11 Caucasian patients with the syndrome of demyelinating polyneuropathy associated with monoclonal IgM autoantibodies with affinity for myelin‐associated glycoprotein. The frequency of Gm phenotypes in the patient group was significantly different from that seen in a normal Caucasian population.