Premium
Recovery of vision after ischemic lesions: Positron emission tomography
Author(s) -
Bosley Thomas M.,
Dann Robert,
Silver Frank L.,
Alavi Abass,
Kushner Michael,
Chawluk John B.,
Savino Peter J.,
Sergott Robert C.,
Schatz Norman J.,
Reivich Martin
Publication year - 1987
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410210505
Subject(s) - positron emission tomography , occipital lobe , deoxyglucose , medicine , lesion , visual field , temporal lobe , striate cortex , nuclear medicine , cortex (anatomy) , ischemia , neuroimaging , visual cortex , radiology , pathology , psychology , neuroscience , ophthalmology , psychiatry , epilepsy
We used [ 18 F]fluoro‐2‐deoxyglucose positron emission tomography (PET) to study serial changes in the local cerebral metabolic rate of glucose in 5 patients with ischemic lesions of the posterior afferent visual system causing homonymous visual field defects. All 5 patients had striking impairment of glucose metabolism in the striate cortex shortly after ictus. In 2 patients, visual field defects abated, and repeat PET scans showed reduced size of the metabolic lesion and improvement of striate metabolism. Three patients did not recover vision, and repeat PET scans did not show improvement. Patients who recovered vision had ischemic lesions outside the occipital lobe, while those who did not experience improvement had primary damage to the occipital lobe itself.