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Preferential loss of large lumbar primary sensory neurons in carcinomatous sensory neuropathy
Author(s) -
Ohnishi Akio,
Ogawa Michiko
Publication year - 1986
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410200119
Subject(s) - sensory system , dorsal root ganglion , fasciculus , sural nerve , medicine , lumbar , anatomy , sensory loss , autopsy , ganglion , lumbar nerve , sensory neuron , nerve root , dorsum , sensory nerve , pathology , biology , neuroscience , surgery , white matter , fractional anisotropy , radiology , magnetic resonance imaging
Morphometric studies at autopsy of a patient with sensory neuropathy associated with small‐cell lung carcinoma showed preferential loss of large‐diameter sensory nerve cell bodies (fifth lumbar dorsal root ganglion), marked decrease of large myelinated fibers in the dorsal root and sural nerve, and almost total loss of myelinated fibers in the fasciculus gracilis.