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Comparison of amaurosis fugax and transient cerebral ischemia: A prospective clinical and arteriographic study
Author(s) -
Hurwitz Barrie J.,
Heyman Albert,
Wilkinson William E.,
Haynes Carol S.,
Udey Carol M.
Publication year - 1985
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410180612
Subject(s) - amaurosis fugax , medicine , amaurosis , cardiology , cerebral infarction , ischemia , stroke (engine) , prospective cohort study , carotid arteries , surgery , mechanical engineering , engineering
We compared the clinical associations, arteriographic findings, and long‐term outcome of 93 patients with amaurosis fugax and 212 patients with focal cerebral ischemia (transient ischemic attacks [TIAs]). The group of patients with cerebral TIAs included a significantly larger proportion of blacks and had a higher prevalence of hypertension than the group with amaurosis. Operable atherosclerotic lesions of the carotid arteries were more often associated with amaurosis (66%) than with cerebral TIAs (51%). The seven‐year cumulative rate of cerebral infarction, however, was less in patients with amaurosis (14%) than in those with cerebral TIAs (27%; p < 0.02). This difference in outcome persisted after adjustment for race, hypertension, and type of therapy. There were no significant differences, however, in the cumulative rates either of recurrent TIAs or of myocardial infarction or sudden death in the two groups of patients.