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Reversible go–no go deficits in a case of frontal lobe tumor
Author(s) -
Leimkuhler M. E.,
Mesulam M.M.
Publication year - 1985
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410180518
Subject(s) - frontal lobe , neuropsychology , lesion , psychology , meningioma , computed tomographic , audiology , medicine , neuroscience , psychiatry , computed tomography , surgery , cognition
A 50‐year‐old woman had been treated for a psychiatric disorder for three years. Findings during the elementary neurological examination were essentially normal. However, a computed tomographic scan revealed a large meningioma in the falx involving the medial aspects of the frontal lobes bilaterally. Neuropsychological examination demonstrated deficits in complex attentional tasks and also many errors of commission in the go–no go test. Following surgical excision of the tumor, her go–no go performance became normal. This patient shows that damage to the medial frontal lobe can cause deficits in go–no go performance, and that these deficits can be reversible following resolution of the lesion.

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