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Galactosialidosis: Low β‐galactosidase activity in serum after long‐term clotting
Author(s) -
Sakuraba Hitoshi,
Iimori Yuichi,
Suzuki Yoshiyuki,
Kint Jos A.,
Akagi Masao
Publication year - 1985
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410180215
Subject(s) - term (time) , medicine , clotting factor , quantum mechanics , physics
Serum β‐galactosidase activity was found to be markedly increased in clotting blood from normal subjects, but patients with galactosialidosis showed only a slight increase of this enzyme activity. Consequently, the β‐galactosidase activity was low in serum after long‐term clotting in patients with this disease. The mechanism of the enzyme activation is unknown. The use of anticoagulants completely inhibited the activation.