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Association between essential tremor and Parkinson's disease
Author(s) -
Geraghty John J.,
Jankovic Joseph,
Zetusky Walter J.
Publication year - 1985
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410170404
Subject(s) - essential tremor , parkinson's disease , association (psychology) , medicine , disease , physical medicine and rehabilitation , psychology , psychotherapist
To examine a possinle relationship of essential tremor to Parkinson's disease (PD), 130 patients with essential tremor were studied. Twenty‐five patients had both essential tremor and PD. These 25 patients were matched for age and duration of PD symptoms with 25 patients who had idiopathic PD. Bradykinesia, postural instability, and gait difficulty were more severe in the patients with idiopathic PD. Degree of tremor, rigidity, and fumctional disability did not differ in the two groups. The prevalence of PD in the population with essential tremor was 24 times greater than expected. This study suggests that some patients with essential tremor have genetically increased risk for PD.