Premium
Stimulus rate determines regional brain blood flow in striate cortex
Author(s) -
Fox Peter T.,
Raichle Marcus E.
Publication year - 1985
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410170315
Subject(s) - stimulus (psychology) , cerebral blood flow , striate cortex , positron emission tomography , photic stimulation , neuroscience , blood flow , stimulation , psychology , visual cortex , medicine , anesthesia , visual perception , cognitive psychology , perception
Intravenous bolus administration of oxygen 15‐labeled water and positron emission tomography were used to measure changes in brain blood flow induced by two modes of photic stimuli over a wide range of repetition rates. These stimuli (patterned‐flash and reversingd checkerboard) were chosen in order to determine whether stimulus luminacne or stimulus frequency was reponsible for previously observed increased in blood flow in the striate cortex during photic stimulation. The response curves of blood flow change as a function of stimuls rate were nearlyl suggest that elementary stimulus variables, such as repetition rate, can have a major effect on local cerebral responses, as measured with positron emission tomography and other radiotracer methods.