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Atypical presentations of pyridoxine‐dependent seizures: A treatable cause of intractable epilepsy in infants
Author(s) -
Goutières Françoise,
Aicardi Jean
Publication year - 1985
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410170203
Subject(s) - pyridoxine , medicine , epilepsy , pediatrics , intractable epilepsy , convulsion , pyridoxine deficiency , anesthesia , psychiatry
We repport on 3 patients with atypical pyridoxine‐dependent seizures. Each had either late onset of convulsions(2 cases)or seizure‐free intervals of up to several months' duration in the absence of pyridoxine supplementation. The findings, taken together with those in 9 previously reported cases, indicate that a trial of pyridoxine shoul be performed in all seizure disorders with onset before 18 months of age, regardless of type.