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Crystalline encephalopathy: Cerebral immunoprotein deposits and isolated angiitis
Author(s) -
Pezeshkpour G.,
Stuart Thomas D.,
Estridge M. N.
Publication year - 1985
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410170120
Subject(s) - polyclonal antibodies , pathology , extracellular , brain biopsy , antibody , computed tomographic , encephalopathy , intracellular , medicine , biopsy , chemistry , immunology , radiology , computed tomography , biochemistry
Brain biopsy specimens from a 38‐year‐old woman with adversive seizures and bifrontal mass lesions evident on computed tomographic scans showed extracellular and intracellular deposits of crystallized protiens. These were morphologically identical to the immunoglobylin crystals seen in reactive or neoplastic plasma cells and by peroxidase‐antiperoxidase methods were found to contrain polyclonal immunoglobulins. In addition, severe angiitis of the intracerebral blood vessels was present.