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Diagnostic importance of immunological markers in lymphoma involving the central nervous system
Author(s) -
EzrinWaters Cheryl,
Klein Michel,
Deck John,
Lang Anthony E.
Publication year - 1984
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410160608
Subject(s) - cerebrospinal fluid , lymphoma , clone (java method) , central nervous system , primary central nervous system lymphoma , immune system , pathology , immunology , virus , medicine , immunodeficiency , biology , dna , genetics
In an elderly woman, lymphoma involved the central nervous system and unusual nonlymphoreticular sites. Cerebrospinal fluid cell surface marker studies revealed a clone of malignant B cells. Studies of peripheral blood demonstrated a systemic disturbance of immune regulation similar to Epstein‐Barr virus infections and the acquired immunodeficiency syndrome.