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Computed tomography of the brain in subacute sclerosing panencephalitis
Author(s) -
Krawiecki Nicolas S.,
Dyken Paul R.,
El Gammal Taher,
Durant Robert H.,
Swift Andrea
Publication year - 1984
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410150515
Subject(s) - subacute sclerosing panencephalitis , atrophy , medicine , brainstem , cerebral atrophy , parenchyma , pathology , cerebrospinal fluid , central nervous system disease , white matter , magnetic resonance imaging , radiology , measles , measles virus , vaccination
Abstract Twenty‐four computed tomographic scans of 12 patients with confirmed subacute sclerosing panencephalitis were studied using standardized techiques of radiological assessment. Abnormalities encountered were of four types–s(1) lateral ventricular dilatation, (2) cerebral cortical atrophy and sylvian fissure widening, (3) low parenchymal attenuation, and (4) brainstem atrophy and cerebellar atrophy‐and of varying degrees. The abnormalities correlated best with the stage and duration of disease, but not necessarily well with the patient's mental state. The fewest radiological abnormalities were encountered in the acute or early stages, whereas more signs of parenchymal disturbances in the form of low attenuations emerged during intermediate periods. Chronic periods were accompanied by atrophic changes in the form of cortical atrophy, ventricular dilatation, and brainstem cerebellar atrophy.