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Hypothalamic mass and gigantism in neurofibromatosis: Treatment with bromocriptine
Author(s) -
Duchowny Michael S.,
Katz Raananah,
Bejar Rafael L.
Publication year - 1984
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410150318
Subject(s) - gigantism , bromocriptine , acromegaly , neurofibromatosis , medicine , endocrinology , lesion , growth hormone , prolactin , surgery , pathology , hormone
Abstract A child with neurofibromatosis exhinbited gigantism and acromegaly in association with a hypothalamic mass lesion. Bromocriptine, 5 mg daily, reduced somatic growth rate and restored biochemical mohesostasis but had no effect on tumor grwoth. Radiation therapy arrested tumor enlargement and stabilized deeriorating visual function.