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Creutzfeldt‐Jakob disease: A case of 16 years' duration
Author(s) -
Cutler Neal R.,
Brown Paul W.,
Narayan Tina,
Parisi Joseph E.,
Janotta Frank,
Baron Henry
Publication year - 1984
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410150121
Subject(s) - disease , creutzfeldt jakob syndrome , medicine , degenerative disease , pediatrics , psychiatry , pathology , prion protein
A 46‐year‐old man with Creutzfeldt‐Jakob disease confirmed postmortem had a 16‐year course of very slowly progressing incoordination and mental deterioration, suggesting Alzheimer's disease. The disease course transformed abruptly into a 7‐week terminal phase of florid Creutzfeldt‐Jakob disease. Dementing illnesses of unknown cause were present in the patient's paternal lineage.