Premium
Nuclear magnetic resonance imaging in multiple sclerosis
Author(s) -
Lukes Steven A.,
Crooks Lawrence E.,
Aminoff Michael J.,
Kaufman Leon,
Panitch Hillel S.,
Mills Catherine,
Norman David
Publication year - 1983
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410130603
Subject(s) - spin echo , magnetic resonance imaging , nuclear magnetic resonance , multiple sclerosis , nuclear medicine , white matter , fast spin echo , signal (programming language) , physics , medicine , radiology , computer science , psychiatry , programming language
Ten patients with definite multiple sclerosis underwent hydrogen nuclear magnetic resonance imaging with a 3.5 kilogauss superconducting magnet, using the inversion recovery and spin‐echo techniques of signal acquisition. Results were compared with high‐resolution x‐ray computed tomography. Spin‐echo images demonstrated abnormal regions as areas of variably increased signal intensity. The contrast between abnormal and normal white matter improved as the intervals between sequential radiofrequency pulses and between pulse administration and signal sampling were increased. Inversion recovery images demonstrated abnormal areas as regions of decreased signal intensity but did not visualize lesions as well as spin‐echo imaging. Spin‐echo and inversion recovery imaging each demonstrated more extensive abnormalities than did computed tomography.