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Normal vitamin E status in spinal muscular atrophy
Author(s) -
Sokol Ronald J.,
Iannaccone Susan T.
Publication year - 1983
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410130318
Subject(s) - sma* , spinal muscular atrophy , medicine , vitamin , atrophy , endocrinology , vitamin e deficiency , vitamin d and neurology , vitamin e , physiology , disease , biology , biochemistry , mathematics , combinatorics , antioxidant
In an attempt to confirm prior reports of vitamin E deficiency in Werdnig‐Hoffmann disease, we assessed vitamin E nutritional status in 11 children and 6 adults with spinal muscular atrophy (SMA). Serum vitamin E levels (10.6 ± 3.3 m̈g/ml for those less than 12 years old, 13.2 ± 4.5 for those older than 12) and the ratio of serum vitamin E to total serum lipids were normal in all patients. Vitamin E nutritional status appears to be normal in SMA, and vitamin E therapy is not indicated.
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