Premium
Observations on the efficacy of propranolol for the prophylaxis of migraine
Author(s) -
Rosen James A.
Publication year - 1983
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410130119
Subject(s) - propranolol , migraine , medicine , anesthesia , migraine disorders
Among 1,036 patients treated for migraine headache between 1973 and 1980, 865 were given a daily maximum dose of 320 mg of propranolol, while 171 served as differently treated controls. At least one year of treatment was prescribed, at the end of which time 84% of the propranolol group reported sustained improvement compared with similar improvement in only 32% of controls ( p < 0.01). The success rate progressively increased during the entire year.