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Mood, vegetative disturbance, and dexamethasone suppression test after stroke
Author(s) -
Finklestein Seth,
Benowitz Larry I.,
Baldessarini Ross J.,
Arana George W.,
Levine David,
Woo Elaine,
Bear David,
Moya Kenneth,
Stoll Andrew L.
Publication year - 1982
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410120509
Subject(s) - depression (economics) , mood , stroke (engine) , sleep disorder , medicine , post stroke depression , mood disorders , disturbance (geology) , dexamethasone suppression test , appetite , rehabilitation , psychology , dexamethasone , psychiatry , physical therapy , insomnia , biology , anxiety , mechanical engineering , paleontology , engineering , economics , macroeconomics
Assessments of mood disturbance and “vegetative” (appetite or sleep) disturbance as well as a single‐dose dexamethasone suppression test (DST) were carried out in 25 randomly selected stroke patients and in 13 nonstroke control patients hosptalized in a rehabilitation center. Prevalence rates of moderate‐to‐sever depression of mood and vegetative disturbance were significantly higher in stroke patients than controls (48% and 52% versus 0% and 8%, respectively), as was the prevalence of abnormal DST results (52% versus 8%). Abnormal DST results were associated with the occurrence of moderate to severe mood, appetite, and sleep disturbances among all patients. In 2 stroke patients, repeated DST results paralleled the clinical course. The DST may be useful as an adjunct to the diagnosis and in monitoring the progress of the common and potentially reversible mood and vegetative disturbances occurring after stroke.