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Involuntary movements in chorea‐acanthocytosis: A comparison with Huntington's chorea
Author(s) -
Shibasaki Hiroshi,
Sakai Tetsuo,
Nishimura Hiroyuki,
Sato Yuji,
Goto Ikuo,
Kuroiwa Yoshigoro
Publication year - 1982
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410120319
Subject(s) - chorea , choreiform movement , psychology , neuroscience , movement disorders , audiology , trunk , physical medicine and rehabilitation , medicine , dyskinesia , biology , parkinson's disease , ecology , disease
The involuntary movements in three patients with chorea‐acanthocytosis (CA) and three with Huntington's chorea (HC) were studied by polygraphic recordings and jerk‐locked averaging technique. Choreic movements in patients with CA were suppressed by mental calculation, voluntary muscle contraction, and instruction to stop them, whereas movements in HC were generally enhanced by these tasks. Backward averaging of the EEG time‐locked to the choreic movement of an extremity or the trunk demonstrated a cortical slow negativity before the movement, similar to the Bereitschaftspotential (“readiness potential”), in cases of CA but not those of HC. Involuntary movements in CA appear to differ from those in HC and might be generated at least in part by a mechanism similar to that of voluntary movement.