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Sleep‐induced nonobstructive hypoventilation associated with diaphragmatic paralysis
Author(s) -
Thorpy Michael J.,
SchmidtNowara Wolfgang W.,
Pollak Charles P.,
Weitzman Elliot D.
Publication year - 1982
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410120318
Subject(s) - hypoventilation , medicine , somnolence , anesthesia , paralysis , apnea , respiratory system , surgery , adverse effect
A patient with adult‐onset spinal muscular atrophy causing mild proximal limb muscle weakness had sleep‐induced nonobstructive hypoventilation due to diaphragmatic paralysis. Nocturnal dyspnea and daytime somnolence were associated with frequent arousals from sleep due to arterial oxygen desaturation. The nocturnal use of a cuirass respirator improved the oxygen saturation, resulting in less disrupted sleep, relief of the somnolence, and improved daytime ventilation.