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Treatment of neuroectodermal brain tumors
Author(s) -
Shapiro William R.
Publication year - 1982
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410120302
Subject(s) - medicine , chemotherapy , radiation therapy , clinical trial , neuroectodermal tumor , resection , surgical resection , primitive neuroectodermal tumor , oncology , pathology , surgery , sarcoma
Prospective clinical trials support the view that malignant neuroectodermal tumors should be treated vigorously using a multimodal approach that includes surgical resection, high‐dose radiation therapy, and prolonged maintenance chemotherapy. Less malignant astrocytomas and oligodendrogliomas should be treated by resection and irradiation. Laboratory research on neuroectodermal tumors has advanced rapidly, providing new data on tumor cell biology and the pharmacology of chemotherapy that directly influence the therapeutic options.