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Multiple sclerosis: Heterology among early T cells and T G cells
Author(s) -
Traugott Ute,
Scheinberg Labe C.,
Raine Cedric S.
Publication year - 1982
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410110212
Subject(s) - multiple sclerosis , immunology , biology , medicine , microbiology and biotechnology
Circulating early T cells and T G cells were estimated simultaneously in 100 patients with multiple sclerosis and 21 controls. The results were analyzed from individual patients, from patients grouped according to disease activity, and from some patients studied longitudinally. Previously documented fluctuations in these two T cell populations were confirmed. By comparing the fluctuations and by examining the distribution of T G cells in suspensions of isolated early and isolated late T cells, it was found that T G cells are a T cell subpopulation distinct from early T cells.