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Eaton‐lambert myasthenic syndrome: Long‐term treatment of three patients with prednisone
Author(s) -
Streib Erich W.,
Rothner A. David
Publication year - 1981
Publication title -
annals of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.764
H-Index - 296
eISSN - 1531-8249
pISSN - 0364-5134
DOI - 10.1002/ana.410100507
Subject(s) - prednisone , medicine , lambert eaton myasthenic syndrome , myasthenia gravis , anesthesia
Three patients with the myasthenic syndrome of Eaton‐Lambert (ELS) were treated with prednisone for 6 and 12 months and more than 3 years, respectively. Muscle strength increased considerably in all, reaching a peak after 3 to 4 months, and was accompanied by simultaneous electromyographic improvement. Reduction of prednisone led to deterioration in all 3 patients; strength was regained when the higher dosage of prednisone was resumed. Prednisone is an alternative form of treatment for ELS, although the mechanism for its action is unclear.